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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIM2 All Species: 32.12
Human Site: S185 Identified Species: 88.33
UniProt: Q9P1W9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1W9 NP_006866.2 311 34190 S185 A K L I D F G S G A L L H D E
Chimpanzee Pan troglodytes XP_528972 440 46715 S314 A K L I D F G S G A L L H D E
Rhesus Macaque Macaca mulatta XP_001104389 311 34180 S185 A K L I D F G S G A L L H D E
Dog Lupus familis XP_548990 409 43442 S283 A K L I D F G S G A L L H D E
Cat Felis silvestris
Mouse Mus musculus Q62070 370 40041 S244 I K L I D F G S G A L L H D E
Rat Rattus norvegicus O70444 326 35984 S192 L K L I D F G S G A V L K D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515486 364 41347 S230 L K L I D F G S G A L L R D T
Chicken Gallus gallus
Frog Xenopus laevis Q91822 323 36946 S190 L K L I D F G S G A L L K D T
Zebra Danio Brachydanio rerio Q9YHZ5 310 35169 S189 I K V I D F G S G A T L K D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.4 98.7 71.6 N.A. 75.1 55.8 N.A. 47.7 N.A. 49.2 52.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.4 99 73.5 N.A. 78.1 67.7 N.A. 57.6 N.A. 63.1 67.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 73.3 N.A. 80 N.A. 80 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 80 N.A. 80 N.A. 80 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 100 0 0 0 0 0 0 0 0 100 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 % E
% Phe: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 100 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % H
% Ile: 23 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 100 0 0 0 0 0 0 0 0 0 0 34 0 0 % K
% Leu: 34 0 89 0 0 0 0 0 0 0 78 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 34 % T
% Val: 0 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _